In the film, Witherspoon plays a by-the-book police officer who is on the run from crooked cops while trying to protect the widow (Vergara) of a drug boss.

As I was the first to tell you, Witherspoon almost knocked out some of Vergara's teeth during filming when she accidently hit her in the mouth with a deer hoof.

"I was trying to cover myself with a deer skin and it flopped over and hit her in the teeth," Witherspoon said. "It was bad…That was like the second day of shooting and I thought she was going to quit. It wasn't funny."

Witherspoon ended up spending a night in the hospital after possibly popping an ovary when Vergara pushed her a little too hard during one of their catfights.

"I really didn't care," Vergara joked during the movie's press junket last week. "I just wanted to make sure she was not going to delay everything, that she was going to show up on the set the next day."

Hot Pursuit is in theaters on May 8.

Former True Blood hottie Rob Kazinsky also got to kiss Reese in the movie. Click the video below to find out why their first take seemed a bit too creepy.

And for even more from the premiere, check out E! News tonight at 7 p.m. and 11 p.m.

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